Col de la Cayolle (el. 2,326 m) is a high mountain pass in the French Alps at the border between the departments of Alpes-Maritimes and Alpes-de-Haute-Provence in France.
It connects Barcelonnette in the Ubaye Valley and Saint-Martin-d’Entraunes.
It lies parallel to the Col d’Allos and Col de la Bonette in the Parc National du Mercantour.
The Var River has its source near the pass.
The road leads to the red-rock Gorges de Daluis.